Publications
Rongqing Pan, Jeremy Ryan, Deng Pan, Kai W Wucherpfennig, Anthony Letai. Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis. Cell 2022 Apr 28;185(9):1521-1538.e18. doi: 10.1016/j.cell.2022.03.030. Epub 2022 Apr 20.
Meng J, Jiang YZ, Zhao S, Tao Y, Zhang T, Wang X, Zhang Y, Sun K, Yuan M, Chen J, Wei Y, Lan X, Chen M, David CJ, Chang Z, Guo X, Pan D, Chen M, Shao ZM, Kang Y, Zheng H. Tumor-derived Jagged1 promotes cancer progression through immune evasion. Cell Rep. 2022 Mar 8; 38(10):110492
Shi S, Gu S, Han T, Zhang W, Huang L, Li Z, Pan D, Fu J, Ge J, Brown M, Zhang P, Jiang P, Wucherpfennig KW, Liu XS. Inhibition of MAN2A1 Enhances the Immune Response to Anti-PD-L1 in Human Tumors. Clin Cancer Res. 2020 Nov 15;26(22):5990-6002.
Ferrari de Andrade L, Kumar S, Luoma AM, Ito Y, Alves da Silva PH, Pan D, Pyrdol JW, Yoon CH, Wucherpfennig KW. Inhibition of MICA and MICB Shedding Elicits NK-Cell-Mediated Immunity against Tumors Resistant to Cytotoxic T Cells Cancer Immunol Res. 2020 Jun;8(6):769-780.
Before 2020
De Andrade LF, Lu Y, Luoma A, Ito Y, Pan D, Pyrdol JW, Yoon CH, Yuan GC, Wucherpfennig KW.Discovery of specialized NK cell populations infiltrating human melanoma metastasis. JCI Insight. 2019 Dec 5;4(23):e133103.
Pan D*, Kobayashi A*, Jiang P*, Andrade LF, Tay RE, Luoma A, Tsoucas D, Qiu X, Lim K, Rao P, Long HW, Yuan G, Doench J, Brown M, Liu XL, and Wucherpfennig KW. A Major Chromatin Regulator Determines Resistance of Tumor cells to T cell Mediated Killing. Science, 2018 Jan 4; pii:eaao1710 doi: 10.1126/science.aao1710. (* Denotes equal contribution)
(Highlighted paper for postdoctoral work)
Jiang P*, Gu S*, Pan D*, Fu J, Li Z, Bu X, Li B, Liu JS, Freeman G, Brown M, Wucherpfennig KW and Liu XL. Signatures of T-cell dysfunction and exclusion predict cancer immunotherapy response. Nature Medicine, 2018 Oct;24(10):1550-1558. (* Denotes equal contribution)
(Highlighted paper for postdoctoral work)
Andrade LF, Tay RE, Pan D, Luoma A, Ito Y, Badrinath S, Tsoucas D, Franz B, May KF, Kobold S, Pyrdol JW, Yoon C, Yuan GC, Hodi S, Dranoff G and Wucherpfennig KW. Antibody-Mediated Blockade of MICA/B Shedding Promotes NK Cell-Driven Tumor Immunity. Science 2018, Mar 30; Vol 359, Issue 6383, pp. 1537-1542) DOI: 10.1126/science.aao0505
Zhang S, Pan D, Jia XM, Lin X and Zhao X. The CARMA3-BCL10-MALT1 (CBM) complex contributes to DNA damage-induced NF-kB activation and cell survival. Protein Cell. 2017 Nov; 8(11):856-860.
Wang A, Ding X, Demarque M, Liu X, Pan D, Xin H, Zhong B, Wang X, Dejean A, Jin W and Dong C. Ubc9 Is Required for Positive Selection and Late-Stage Maturation of Thymocytes. J Immunol. 2017 May 1; 198(9): 3461-3470.
Pan D, Jiang C, Ma Z, Blonska M, You MJ and Lin X. The role of MALT1 in EGFR induced NF-kappaB activation and EGFR associated lung cancer progression. Oncogene. 2016 Feb 18; 35(7):919-28.
Pan D*, Zhu Y*, Zhou Z, Wang T, You H, Jiang C and Lin X. CARMA3-BCL10-MALT1 -mediated NF-kB activation contributes to HRE2-assocaited tumor malignancy in breast cancer. Mol Cancer Res. 2016 Jan ;14(1):93-102. (* denotes equal contribution)
Wang T, Pan D, Zhou Z, You Y, Jiang C, Zhao X and Lin X. Dectin-3 Deficiency Promotes Colitis Development due to Impaired Antifungal Innate Immune Responses in the Gut. PLoS Pathog; 2016 Jun 9;12(6): e1005662.
Pan D and Lin X. EGFR-activated NF-kappaB Signaling and Its Role in EGFR-associated
Tumors. Cancer J. 2013 Nov-Dec;19(6):461-7.
Wang A, Pan D, Lee Y, Gustavo M, Feng XF, and Dong C. Cutting Edge: Smad2 and Smad4 regulate TGFbeta-mediated Il9 gene expression via EZH2 displacement. J Immunol. 2013 Nov 15; 191(10):4908-12.
Pan D, Hu J, Ma Q, Pan W and Li M. Diversity and prevalence of the C-terminal region of Plasmodium falciparum Merozoite Surface Protein 1 in China. Acta Trop. 2010 Dec; 116(3): 200-5.